Pain Management DNA, Pain Medications including Opioids and Cannabis – Inagene Diagnostics Inc.

You are one of a kind, and so is your response to medications.

Inagene helps you find out if a medication is likely to work well for you, or if a different medication at an adjusted dose would work better with less side effects before you even start your prescription. Gain life-long insights into your treatment journey for pain and mental health conditions with a simple 5 minute cheek swab test!

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Gain life-long insights to help you find the best possible treatment plan for you.

Whether you have physical pain or or mental health concerns, genetics play a major role in how our bodies respond to different medications. The Personalized Insights™ online report delivers your unique recommendations for over 120 medications for pain and mental health conditions in an easy to use, interactive online report that is updated with the latest research every 6 months.

Interested to see if we test for a medication your are currently, or have been on? Take a look at the medications we test for here.

Designed to be easy to use, wherever, whenever, at your fingertips.

You and your healthcare team always have quick and easy access to vital information needed to optimize your treatment at any stage.

Having surgery or find yourself in the emergency department with an injury? Use the “search” function to look up the specific medications being offered to help manage your pain.

Considering medications as part of your treatment for depression? Create a customized report for antidepressants to evaluate which ones are most likely to work best for you BEFORE starting treatment.

Whatever the situation, Inagene Personalized Insights™ makes it easy to take charge of your health and well-being, and feel better, sooner.

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The Inagene Personalized Insights™ Test provides answers to important questions like these:

What gene variants do I carry that may impact my response to medications?

What medications will work best for me?

Which medications should I avoid altogether?

Do I have an increased risk of side effects with certain medications?

Do I need a different dose of certain medications than most?

Is there an alternative type or dose of medicine that would work best for me?

Our Mission:
Help individuals and their healthcare providers determine which drug and dose will work best, with less trial and error.

Mental health conditions and pain are closely linked.

Those suffering from depression are 3 times more likely to develop chronic pain, and those with chronic pain are 3 times more likely to have depression or anxiety. There is also significant overlap in many of the medications that are used to treat physical pain and mental/psychological health conditions. Inagene is here to help you find the best treatment plan based on your unique genetic profile, with minimal "trial and error", so you can feel better, sooner.

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Said they were “extremely satisfied” with the report they received

Said the drug recommendations were “extremely clear and easy to act on”

Said they believe their past experiences with medications would have been better if they had these results sooner

Believe this test should be taken “before you start any medications for pain or mental health conditions"

Your test saved my son’s life.
He had tried several medications for depression without success, and had become hesitant to try new medications because of negative previous experience. The doctor had put him on a new drug, and he was having real problems with massive mood swings and aggression. I remembered reading that this particular medication could increase cortisol levels, which was causing the aggression.
When we got the test results they were very revealing, and my son recognized a bunch of things from his previous experience. He was taken off of the drug and almost instantly the aggression subsided. He is now on a different drug which he is tapering off on. It is like two different people. Without this test Lord knows what would have happened - assault or relapse.
                                                                                            Father of Inagene Client, Toronto, Ontario

After taking the test, my doctor and I are now able to avoid certain medications that we had been considering for me. Having the test results makes me feel so much more secure because I know now I won’t have to suffer through medications that I otherwise would have had to. I’m really glad you (Inagene) are doing this - I know it will help a lot of people. I would definitely recommend it to anyone who is trying different medications that don’t seem to be working.
                                                                                                                            Inagene Client, Canada

What I would say to people thinking of taking this test is “Do it - you will get a lot of great information and it can really help in you and your doctor in deciding which medication you should take. I am really happy with it and the information I was given – it was the right decision for me. It all went very smoothly and was easy to do.
                                                                                                                                Kevin, 38, Ontario

If my doctor and I had this information 20 years ago many of the medications I have been prescribed would not have been, and that time wouldn’t have been wasted suffering on a medication that wasn’t compatible with my DNA when an alternative that was compatible could have been tried. The test helped us adjust the dosage of my antidepressant, and gave us new antidepressant treatment options to try that are compatible with my DNA. It has also already saved me money in experimenting with cannabis treatment because my doctor and I now know what cannabinoids to try. With so much trial and error in prescribing antidepressants, not only will chronic pain and mental health patients benefit with testing prior to being treated, but it will also benefit doctors, costs, and the environment. If this pandemic is teaching us anything it is that we must move forward using the technology we have now!
                                                                                                                                Lorraine, Ontario 

My daughter has struggled with depression and anxiety for the past 4 years. When first diagnosed we tried many medications with varied results, some worked but the side effects were too great to continue, and others didn't work at all. The effort and time to change medication is tremendous, and an added stress that someone going through anxiety and depression doesn’t need. When I learned about the Inagene test I was hopeful it could be the solution. I spoke to my daughter's doctor who also supported getting the test, as she believes this is the future of medicine. The test kit came quickly, and was extremely easy to use. The report was easy to understand and the results confirmed the category of drugs we were using were not compatible with my daughter’s DNA. The report helped us find a different drug, and her doctor switched her over, leading to a great result! Then my husband, who had side effects from his current anxiety medication, tried switching to her medication at the doctors recommendation (as they share the same DNA) and he had similar positive results. Overall we were extremely impressed with the ease of interpretation and depth of the results, provided in an easy format that you can share with your doctor. Updates are also sent to us when new medications are added. The Inagene test has had a positive impact on our family. We recommend it to anyone who requires medication for anxiety and depression as it will simplify their journey.
                                                                                                                            Traci, Vancouver, BC

My 91-year-old dad has suffered from increased anxiety and depression recently and had asked his GP to increase his dose or to prescribe him another anti-depressant. He had also been taking clonazepam for years, but his GP recently decreased his dose due to risk of falls in elderly. My dad was unhappy and worried that the changes to his medication might make him feel worse instead of better. We ordered the Inagene test kit, and the report revealed that the antidepressant (SSRI) he was on was not ideal for him. His GP shared the report with the Pharmacist, who recommended switching my dad to another SSRI based on the Inagene test results. He said that without the report he would have suggested a different antidepressant, and he was very happy he didn’t do this as the report showed that drug had a ‘red’ warning for my dad so would probably have resulted in a negative experience. Both the GP and pharmacist were very impressed with the simplicity of the report and said they wished other patients had access to this type of information. My dad is now doing much better on his new medication. The test saved us so much stress of back-and-forth to the GP/pharmacist (during COVID and considering dad’s mobility issues) and allowed a medication change to be made that was most appropriate for my Dad. This test provides an amazing tool that will save money, time and reduce stress/anxiety for patients. Based on this experience I have now ordered the kit for my mother as well! Daughter of Inagene client – Toronto, Ontario

Who can benefit from taking the Personalized Insights™ test?

Anyone who is taking or considering taking medications for pain or mental health conditions.

The test may be especially beneficial if you have experienced any of the following:

Lack of effectiveness with medications (poor response)

"Sensitivity" to medications or unusual side effects

Taking multiple medications

Requiring unusually low or high doses of medications

Get Started With The Inagene Personalized Insights™ Cheek Swab Test

Inagene’s Personalized Insights™ Cheek Swab Test takes less than 5 minutes to do and starts you on the path to knowing more and feeling better through Personalized Medicine. Personalized Insights™ is the most comprehensive pharmacogenetic test in the world for pain and mental health, testing for 55 genes and 116 variants that have been shown to impact individual responses to 120 commonly used medications.

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At Inagene, we are doctors, researchers, scientists, entrepreneurs, and patients ourselves.

We are passionate about harnessing the power of genetics and personalized medicine to transform the lives of people who suffer from pain or mental health conditions of any kind. Located in Toronto, Ontario, Inagene is 100% Canadian owned and operated.

About Us

Your Privacy is Our Promise

At Inagene, we believe that personalized medicine should never mean an invasion of privacy, and protecting the security of your personal data is of paramount importance. Inagene operates in full compliance with Canadian Data Protection regulations, including the Personal Information Protection and Electronic Documents Act (PIPEDA) and all Canadian Provincial Privacy Regulations.

Inagene will never share or sell your data to third parties, and comprehensive physical, electronic and procedural safeguards are in place to protect against unauthorized use, access, alteration, duplication, destruction, disclosure, loss or theft of your personal information. Additionally, Canadian legislation prevents employers, insurance companies or anyone else from asking you to disclose your genetic test results.

Learn more about our commitment to protecting your genetic data through our rigorous privacy and security policies. 

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Have questions about insurance coverage?

Some private insurance plans will cover pharmacogenetic testing. Learn more about applying for reimbursement for your test through your insurance provider here.

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Have questions?

Visit our FAQ page for answers to the most commonly asked questions.