Frequently Asked Questions - Healthcare Practitioners – Inagene Diagnostics Inc.

Frequently Asked Questions - Healthcare Practitioners

General

Who can benefit from Pharmacogenetic testing with Inagene Personalized Insights™?

Inagene Personalized Insights™ is designed for anyone who is interested in understanding which drugs are likely to work best to treat their pain or mental health condition. It can also be particularly helpful for patients with a variety of other conditions (eg. cardiology, oncology, gastroenterology). Personalized Insights™ is also useful for people interested in knowing whether cannabis may be a good treatment option for them. Pharmacogenetics testing may be helpful even for those who currently do not take any medication as a proactive measure by finding out which medications would work best for you best on your genetics.

Do patients need the test to be ordered by a prescriber?

No, patients can order the test directly from Inagene.com, or purchase it directly from select pharmacies.

Does Inagene offer a payment (installment) plan?

Yes. When completing an online purchase at inagene.com, patients are provided with the option for payment via four instalments.

Are PGx tests covered by insurers?

Many private insurers are now covering PGx testing, however, whether someone has coverage (and under what circumstances) is typically dependent on the specific plan provided/selected by/from the employer, and, in some cases, the specific plan options selected by the employee. PGx testing is often covered under Health Care Spending Accounts, and is covered under some paramedical benefits under “diagnostic tests”. For more information and resources click here.

How long does it take to get the results?

Results are posted to Inagene’s secure portal within 7-9 days of receiving the sample at Inagene’s Toronto-based lab.

Why are some medications not included in the test?

If a drug is NOT included on our test(s), it is because no drug-gene interaction has been identified that is supported with a sufficient level of evidence. Personalized Insights™ tests include all medications that have recognized gene-drug interactions supported with a sufficient level of evidence.

The PrecisionRx test includes some pain and mental health medications, but not as many as are included in the Precision Pain and Mental Health test – why?

Inagene Personalized Insights™ Precision Pain and Mental Health is designed to provide maximal insights for those being treated for pain and/or mental health-related conditions, and tests for 55 genes and 116 variants specifically linked to responses to the common medications used to treat these conditions, including those that are preliminary in nature. Including ONLY the genes and variants linked to these conditions allows this test to provide deeper insights on more medications for pain and mental health than other pharmacogenetic tests. This test includes some preliminary data, as well as a full cannabis/cannabinoid panel, and research variants on risk of cannabis and opioid dependency. Personalized Insights™ PrecisionRx includes only those drugs and recommendations supported with higher levels of evidence (Level 2B and above), resulting in the inclusion of roughly half of the pain and mental health drugs that are included in the Precision Pain and Mental Health test.

How do I open a HCP Portal Account?

Go to patients.inagene.com, click on “Register” and follow the instructions provided. Make sure to select “Healthcare Provider” as your user type. Detailed instructions can also be found here.

How long does counselling of patients on results typically take and what is involved?

Counselling on PGx results can typically be done within 20-40 minutes. Inagene’s reports are uniquely designed to be simple for consumers to understand, which helps minimize counselling time required. Inagene provides training support, counselling tools and detailed FAQ documents to streamline the counselling process. Find examples of our patient counselling materials here (links coming soon)

Where do I access training and counselling support tools?

Training resources and counselling support tools can be accessed at any time via the TOOLKIT section on your Healthcare Provider portal account.

How is patient privacy assured?

Patients must consent to the genetic testing being performed, and healthcare providers ordering/registering the test must indicate that they have the patient’s permission to order the test and that the patient has been provided with access to Inagene’s Privacy and Consent Policy. Healthcare providers sharing results with other HCPs are prompted to confirm that they have the patient’s consent to share access to the results. Patients can view who has access to their online report via the Access Overview and can remove access at any time.

Can ordering a PGx test affect a patient’s ability to get health insurance?

No. Inagene does not share or sell data to third parties, and comprehensive physical, electronic, and procedural safeguards are in place to protect against unauthorized use, access, alteration, duplication, destruction, disclosure, loss, or theft of our clients’ personal information. Canadian legislation prevents employers, insurance companies or anyone else from asking individuals to disclose their genetic test results, and prevents test results from being used to deny the provision of insurance benefits.

If I’m a Prescriber

How would I get the results if my patient ordered a test themselves or from a pharmacist?

It is important to have clear communication with your patients to ensure they inform you about their choice to order one of our tests. The Inagene Portal system allows patients to automatically share access to their online report with you at the time they register their buccal swab sample, or at any time after receiving their results, using your email address. Alternatively, a PDF version of the report can be emailed, printed, and/or faxed to the prescriber. You can also provide your patient with a note (downloadable here) that your patient can share with their pharmacist to give you easy access to their results.

How do I explain to my patient which test will be best for them?

It is important to determine what your patient’s goals are for ordering a pharmacogenetics test. If your patient is ONLY wanting information on how their genetic profile can impact their response to pain and mental health drugs then the Personalized Insights™ Precision Pain & Mental Health test is the best option (retail price $299).

Patients who would benefit from insights to inform treatment across other (multiple) therapeutic areas have two options:

● The Personalized Insights™ PrecisionRx test predicts responses to >160 commonly used drugs for multiple therapeutic areas (e.g. oncology, cardiology, gastroenterology. some mental health and pain medications are also included). (Retail price $299)

● The Personalized Insights™ PrecisionRx ULTRA package offers BOTH PrecisionRx and Precision Pain & Mental Health at a significantly discounted price (retail price $399). Both reports are provided with only one cheek swab test. If you have any further questions or concerns you can email our customer service at info@inagene.com

How do I bring up PGx testing with my patients?

If you have patients who you think might benefit from pharmacogenetics testing, you may wish to provide them with some of our promotional/educational materials to learn more. Find examples of the patient materials we offer here (link to materials coming soon).

If I’m a pharmacist

What resources are available for partner pharmacies to promote the pharmacogenetic testing service to clients?

Inagene provides a full suite of promotional tools to support partner pharmacies in promoting their new pharmacogenetic testing service to clients/patients, and to prescribers in the surrounding area. This includes videos for in-store monitors/counselling rooms, posters, patient handouts, a bank of sample social media posts/GIFs, and information that can be emailed to patients and/or prescribers. All materials can be co-branded with your pharmacy’s branding and contact information. Find examples of our partner resources here.

How are results shared between the pharmacist/HCP and the patient?

Either the HCP/pharmacist or the patient can register the test kit on the Inagene Portal (using the unique 14-digit code found in the test kit). The option is provided to share access to the results with another party at the time the kit is registered, by including the individual’s name and email address (e.g. the pharmacist can cc the patient or vice versa at the time of kit registration). The individual who registered the kit receives notifications and access to the results when ready, as does the individual who was cc’d. Results can also be shared at any time by clicking on “Share/View Report Access” and “Add New Access” and filling in the required information. The patient can view who has access to their online report via this feature and can remove access at any time. Please consult this video/ cheat sheet with tips on how to easily share reports (links – coming soon).

How are results shared with prescribers?

Results can be shared with other HCPs involved in the patient’s care at any time once they have been posted to the portal account. A PDF of an “HCP Report” can be downloaded and emailed or faxed directly from the online report itself. Access to the online report can also be shared from the Reports Page on the Portal by clicking on “Share/View Report Access” and “Add New Access”, and filling in the person’s contact information. Patients and pharmacists who are sharing access to the online report are also presented with the option to answer 5 drop-down questions to generate a Personalized Summary Letter, directing the reader to the most pertinent information regarding the patient’s results. Patients can view who has access to their online report via the Access Overview, and can remove access at any time.

What if patients or prescribers have questions that I am unable to answer?

Frequently asked questions to support patient consults are available at any time on the reports view of the patient report and are updated regularly. The “chat” function is also readily accessible from within the portal system at any time. Inagene’s support staff and geneticists are available to support partner pharmacies and clinics with questions as needed. Reach out with questions at any time at info@inagene.com.

Can I offer my patients/clients a discount?

Although the margin between the wholesale price and retail price of the kit supports the pharmacist's time in providing a consult to the patient/client, partner pharmacies are free to use a portion of the margin (difference between the wholesale and retail price) provided to offer their patient a discount if desired. Contact info@inagene.com to arrange for an automatic discount on online purchases based on the use of your unique promo code.

My patient wants to discuss the Personalized Insights™ test with their prescriber before ordering. What information can they provide to the prescriber?

Click here to download a Summary for Prescribers (with helpful links and Inagene contact info embedded) that can be provided to the patient to send/take to their prescriber.

Are there are resources available for pre-test counselling?

We are currently working on developing some counselling materials, subscribe to our newsletter to find out when these will be available.