Not every person will respond to pain medication the same way.
How well medications work for you may be impacted by your DNA.
>99% of people have gene variants impacting their medication response. 1
1. McInnes, G., Lavertu, A., Sangkuhl, K., Klein, T. E., Whirl-Carrillo, M., & Altman, R. B. (2020). Pharmacogenetics at scale: An analysis of the UK Biobank. Clinical Pharmacology & Therapeutics. https://doi.org/10.1101/2020.05.30.125583
Knee and hip surgery patients reported less pain on average when pharmacogenetic testing was used to inform treatment. 2
2. Hamilton WG, Gargiulo JM, Reynolds TR, Parks NL. Prospective Randomized Study Using Pharmacogenetics to Customize Postoperative Pain Medication Following Hip and Knee Arthroplasty.J Arthroplasty. 2022;37(6S):S76-S81. doi:10.1016/j.arth.2022.02.037
Pharmacogenetic testing can reduce likelihood of side effects by 30%. 3
3. Swen JJ, van der Wouden CH, Manson LE, et al. A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study.Lancet. 2023;401(10374):347-356. doi:10.1016/S0140-6736(22)01841-4
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Click to view how different people may respond to common pain medications.
Real testimonials from Inagene customers
Small differences in your DNA can have a real impact on your medications ability to reduce pain.
Bonnie validated her difficult past experiences with opioids
The test results are entirely consistent with my past experience...I feel validated seeing them. I spent years trying different drugs, and was told the problems were in my head, and I felt like no one believed me. I can’t help but wonder what it would have been like if ten years ago I had taken the Inagene test, and then started to try medications with this information available to all of my doctors.
Richard has chronic pain and depression
I cannot put into words how valuable this is to me.
To wake up in the morning and my hands and feet aren’t on fire or screaming at me, to look forward to working again, to be able to do stuff with my kids....I would pay all the money I have for this chance at life again.
A pain specialist on his patient’s fibromyalgia
She was “extremely happy” with the comprehensiveness and utility of her Personalized Insights™ test results, particularly as they have directly impacted her treatment plan going forward. Discontinuing a medication (which had been classified as Do Not Use) was seen by my patient as a real bonus, as she thought she would be paying out of pocket for it for another 10 years!
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